ncRNA name | hsa-miR-27b |
ncRNA Category | miRNA |
Disease name | diabetic retinopathy (DR) |
Species | Homo sapiens |
Tissues/Cell_line | serum; human umbilical vein endothelial cells (HUVECs) |
Methods | TaqMan miRNA assay, transfection, luciferase reporter assay, ELISA |
Expression pattern | up-regulated |
Functional description | miR-320a and miR-27b are associated with new onset of retinopathy and progression of retinopathy. They may have clinical utility given their established links to angiogenesis, including the translational control of TSP-1 by miR-27b and its reduced endothelial secretion by miR-320a. |
PubMed ID | 26395742 |
Year | 2016 |
Title | Angiogenic microRNAs Linked to Incidence and Progression of Diabetic Retinopathy in Type 1 Diabetes. |
Drug-related ncRNA | NO |
Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.